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100 is the New 30: Dr. Jeffrey Gladden on the 5 Circles of Longevity, AI Workforce Shifts, and Digital Brains

Episode 65 · 11 March 2026 · 1 hr 9 min

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100 Is the New 30: Dr. Jeffrey Gladden on the 5 Circles of Longevity

100 is the new 30 is Dr. Jeffrey Gladden's mission: the health and vitality of a 30-year-old at 100, plus a lifetime of wisdom. Randy Lorensen, Dr. John Oberg and Anthony Marino ask him about his five circles of longevity, the stress that ages us, and which popular longevity tools are worth it. The Abundance Briefing covers the happiness U-curve, a fruit-fly brain emulation and Anthropic's report on AI and jobs.

What if you could have the health and vitality of a 30-year-old when you reach 100? In this episode, Dr. John Oberg, Randy Lorensen, and Anthony Marino are joined by world-renowned longevity expert and cardiologist Dr. Jeffrey Gladden to deconstruct the "symphony of longevity". We explore why aging is an exponential problem that requires an exponential solution, and how optimizing your nervous system is the ultimate "inside job" for living young for a lifetime.

Before diving into the science of agelessness, the trio breaks down the Happiness U-Curve, questioning why the 40s are often a "nadir" of satisfaction and how the data suggests our best years may actually be ahead of us. We also look at the bleeding edge of technology with Eon Systems’ recent digital upload of a fruit fly brain and a new Anthropic report detailing how AI is reshaping the professional landscape—shifting the focus from simply "earning" to "owning" in the new economy.

Whether you’re in your 20s looking at the long game or in your 70s ready to "re-architect" your environment, this conversation moves past surface-level health tips to address the psycho-spiritual foundation of true abundance.

Dr. Jeffrey Gladden, the Happiness U-Curve, and Sauna and Cold Plunge Benefits

What you'll discover:

  • The "300-year-old mind": why longevity is about wisdom and inner peace as well as a young body
  • Dr. Gladden's five circles of longevity, and why you start by "deconstructing" yourself
  • Taking off the "backpack" of stress and trauma, and the mogul-skier mindset
  • Sauna and cold plunge benefits, vibration plates and red light: what's worth doing
  • Why a clean full-body MRI isn't the whole cancer-screening story, and protein without accelerated aging
  • In the Abundance Briefing: the happiness U-curve, Eon Systems' fruit-fly brain, and Anthropic's AI jobs report

This episode is for educational purposes only and isn't medical advice.

Timestamps

  • [00:00] The Abundance Briefing: the happiness U-curve and why life satisfaction rebounds after 50
  • [02:11] The "invincibility" of youth and modern doomerism
  • [04:49] Eon Systems' whole-brain emulation of a fruit fly
  • [08:31] Anthropic's report on which jobs are most exposed to AI, and "earn vs. own"
  • [15:19] Break: AG1
  • [16:11] Welcome, Dr. Jeffrey Gladden: making 100 the new 30
  • [19:05] The 300-year-old mind: vitality plus accumulated wisdom
  • [24:50] The five circles of longevity
  • [36:12] Taking off the "backpack": the stress and trauma that age your biology
  • [41:15] The mogul-skier mindset: using the nervous system to move through life with stillness
  • [43:00] How to get started: the Gladden Longevity podcast, the book and "deconstructing" yourself
  • [45:46] Things that are universally good: BrainTap, molecular hydrogen and the basics
  • [48:32] Vibration plates, red light, saunas and cold plunges: what the data says
  • [55:35] The full-body MRI "lie" and testing for circulating tumor cells
  • [58:58] Perfect Aminos vs. high protein: building protein without accelerating aging
  • [1:01:51] How the Gladden Longevity program works across all five circles
  • [1:04:30] Continuous glucose monitoring vs. insulin testing
  • [1:07:13] The takeaway: answers for a longer, more abundant life, and where to learn more

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About Dr. Jeffrey Gladden

Dr. Jeffrey Gladden is a cardiologist and the founder of Gladden Longevity in Dallas, where his team works with clients across what he calls the five circles of longevity. He is the author of 100 Is the New 30: How Playing the Symphony of Longevity Will Enable Us to Live Young for a Lifetime, and he hosts the Gladden Longevity Podcast.

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Meet the hosts: Randy Lorensen · Dr. John Oberg · Anthony Marino

Transcript

A full transcript is below. It was generated automatically from the episode audio, so expect some spelling errors in names and terms.

[00:12] week's episode of Tales of Abundance. Uh, let's jump right into the abundance briefing. Anthony, you had a topic about the happiness U curve and how why life gets better after 50. It comes from a Psychology Today article that uh it you know credited the Brookings Institute and some research they did. You want to jump into that and tell listeners what you found and what why it's interesting? — Yeah. Um so that this happiness curve breaks um you know levels of hap quote unquote happiness whatever the definition of happiness is into you know people in their 20s 40s 50s 60s and beyond. And what the study says is that people are happiest when in their 20s, they're least happy in their 40s, but then they tend to bounce back in their 50s, 60s, and beyond. And and I there there two things that one is seems pretty obvious that at least happy in the in their 40s may and you guys can weigh in on this. You know may have to do with career stress and family having kids or not achieving you know the things that you wanted to achieve and having a negative outlook uh on your future as well as you know negative feelings about the past. But what struck me the the most was that people are happiest in their 20s.

[01:37] boy, that just doesn't feel right to me right now in this day and age. May maybe this was true before, but would you guys agree that when you look around and you see the news and you know the stress of uh you know kids getting out of college, you know, not necessarily having the real career opportunities that they once had and inability to own a home and not getting married and not having kids and so on and so forth. I don't know. I just that just struck me as maybe it was but now it isn't. I don't know. What do you guys think? I mean, there's certainly some of that, right? Like young kids and not being able to buy a home and, you know, there is some dumerism going on there, but they're also young and happy and having a good time and, you know, their body's still generally healthy. So, you know, and there is there there is that whole thing about just being a kid and thinking you're unvincible that I think is also playing in — Yeah, maybe maybe there's a sense of naive that, you know, I can I can, you know, I can accomplish anything. But I don't know. It just like like I said, that's something that I I just had a hard time uh swallowing. Conversely, you know, from a personal standpoint, I can certainly say that as you know, you you get old and you start to become more open-minded and kind of uh able to handle the stresses of the day or the the uh the surprises that that come.

[03:10] Yeah. you you it seems to be that you would become more more settled and more um you know happier later later in life and satisfied with where you are most mostly because you really can't do anything about what you don't have but you can certainly you know enjoy what you do have so yeah I can see how that — I mean this is this is the the study that came from the Gallup world poll where this was derived from this this study is about 10 years old or so at least the Brookings Institute report is and so I think it's yes what are all the things causing stress and then what happens to those stressors and it some of those stressors I think go away and some of it becomes our ability to handle the stress right and you can see that that U-shaped curve changes and there's difference for you know married satisfaction versus single versus all data and what happens and so there's um yeah I mean it's interesting data right but I think this really what it means is that stress impacts happiness and as you can do things to handle stress more effectively and reduce stress in your life. That's, you know, those are helpful things. And so there's a there's a scatter chart here that's really interesting too at the beginning that is just shows like it's a little different in each country where the turning point — Um and then in terms of like overall happiness, uh you know, pretty interesting here. Um — yeah, but what's what's what's great here is that um most people would say my best years are behind me, but the data suggests that that isn't true. So that's the good reason we can we can close on that. So — more more abundance ahead. And I think that's uh yeah, more abundance ahead.

[04:47] That's great. — there's hope. All right, our second topic is uh a company by the name of Eon Systems claims it has uploaded a fruit flies brain into a digital body. So if you think about Star Trek and Transporter technology, they were transporting everybody's brain and everything else into their own body, but here they're putting it on a computer. So I don't think we're there yet, but is this a step on the way? And to give you some perspective, researchers uh mapped the entire flu flute fruitfly conneto uh which is 140,000 neurons and 50 million synopsis. Now I read a thing over the weekend. I forget what it was. It's a fraction of what a human brain would be, but this is the first step. And what you know talking about abundance, what does this open up, right? Um, you know, and I I think of Ray Kurszswwell talking about wanting to upload his consciousness and live forever and he's been predicting this has been coming. Well, this seems like it's a step on that, you know, on that path. But, you know, what other experiments does this allow us to do instead of having to take humans if you can upload people's consciousness? Uh, whether it's humans or animals, I mean, is it a new drug discovery? Um, you know, I I don't know. What What do you guys think of this?

[06:14] — You're taking me back 30 years. — Could they could Could they have picked anything smaller to work on? — Well, here's the deal. So So 30 35 years ago when I was doing biology for real, you know, we use fruit fries to experiment all the time because of, you know, a whole number of reasons. And so what what I wonder about and I hope is true is this allows us to do much faster broader data with less steps in terms of running simulations for things to see what likely outcomes are. And if we can do with a fruitfly then hopefully we can at some point do this with other brains so that human testing becomes less risky. We can do more we can find more problems before it really impacts humans and and the and the research cycle hopefully speeds up with much better data was my hope. I don't know if any of that's true or not, but uh that would, you know, that would certainly be something I would hope coming out of this is we can test faster, test more, and reduce the risk of testing and the cost of testing, too. — Yeah. And Anthony, I think it's like it's a fruitly now, but the next is a mouse, right? And then the next is a bigger animal. And and they got to work their way up. I mean, they got to they got to start somewhere. I I still think it's it's pretty amazing. It's a long ways from being able to upload a human brain, but it seems like — it's more than it's more than amazing that science is able to how many how many hundreds of thousands did you say neurons and synapses going on on something so tiny that they can figure that out? I'm absolutely amazed at what science is doing. I just — in biology has used this for decades, right? They use and they use it because they're cheap. they can do it in huge numbers and fruit flies last like a couple weeks like and so and they have it I think I think the overlap with the human genome is like greater than 50%.

[08:04] And so all those things make it a very interesting starting place for for — or a starting place is the wrong term an interesting milestone for for research — for sure. Yeah, and it should be mentioned. I don't this hasn't been peer- reviewviewed yet or you know I don't think anybody else has recreated it but uh but very very interesting. So John, you've got an anthropic article about the future of work. You want to share that with listeners? — Yeah, super cool. Like I just I'm I'm constantly thinking about like what does AI mean for uh you know the future? What does it mean for the future of our kids? What does it mean for the future of [clears throat] work? I think those are questions that are really, really important. And so, Enthropic put this article out on March 5th of this year that went through how they're going to measure early evidence of AI's impact. And the things that they're saying here aren't going to be a surprise to the three of us. Like, they're they're going to find a new way to measure AI's impact on the workplace. Okay, that's cool. Like, we can agree hopefully over time how to measure this stuff. They say that AI is a long way from reaching its capability. I think we all know that. uh you know they say that workers that are most exposed are going to be professionals and they say that the most at risk from their research says they're going to be older female more highly educated more highly paid like I think that's worrisome and and notable and that there's no systematic uh increase in unemployment for those highly exposed workers today though there is evidence of hiring younger workers has slowed down in these exposed occupations and this is the cool part like it goes through and gives a chart of what those exposed theoretical occupations are and what they're actually observing. And so and and the the shapes of those two things are fairly similar. And it's things we've talked about before where it's like, you know, ground grounds maintenance is less impacted than computer, math, architecture, and engineering. Um, and the impact, you know, is likely coming. So I it's just I think it's these are some things to watch out for. To me, they're also signals signals of where to look for future abundance. Like as you look through kind of industrialization changes and information age changes, you can kind of see where the economy is moving. And I think this is one tool that people can use to see where the economy is moving to identify opportunities for their future. And you know, one of my friends who's in in private equity said this really really smartly in the last week. He said, "Going into the future, people are going to have to learn how to earn in the new economy or how to own in the new economy." And I think that's probably been true for most economies, but earn or own is a great mental model for how to think about where to identify opportunity in in the kind of changing economy. So that's what I got from it.

[10:52] — Yeah, I know. This is just, you know, there's so much opportunity and there's so much excitement with all the technology and what could happen with AI and robotics and everything else going on. Uh, but it is also makes you wonder, you know, I I've had five or six people talk to me in the last week just kind of asking the question like, should I send my kids to college or what should I be doing with my kids? I mean, I was talking to a friend yesterday. His son's 11 and I don't think it's ever even occurred to them that he wouldn't go to college, right? They've got a college fund and he's like, I don't think by the time he's there this is going to be and you know it's a it's scary for people I think entering the job market. This goes back to what Anthony was talking about 20somes and and all of that. But man, I think I think we just got to remind ourselves that everything is getting easier and I don't know where it's going to go. And I think you have to be adaptable and ready for what's coming. But if there's robots and AI and everything else that's just making life that much easier and creating breakthroughs, then we'll figure out something to do. Human I mean technology it might be a little bloody in the meantime, but there will be something for us to do. I think moving forward — there'll be there's a lot of abundance on the way. I think 11 year olds might have it a little bit easier today than the people who are in college today. I think people are in college and early career today have to probably be a little bit more thoughtful and deliberate about the direction they want to head. In fact, I I talked to a group of college students this morning and had them read this article so they can start thinking for themselves about what's going to happen after they graduate. And so I think, you know, part of my role, self-proclaimed, right, is that I want to go out and help people navigate this stuff for the college students that are kind of in my in my sphere. And so how can I help them is by helping them be thoughtful about it. like how do how do they see the changes as they come and kind of tool themselves for the coming — I do believe it's going to get bigger and better.

[12:52] — Yeah. And I think what what you have to think about in terms of, you know, what's what's happening the the the donut, not the whole, right? I think AI is the whole, you know, that's just one of the things that's going on. The donut is, you know, the the entire environment. And you know, man, if you will, not being derisive, has been pursuing improvements in productivity since the beginning of time, right? And that's that's what you have to be conscious of is, you know, the one that struck me on your chart, John, [snorts] it was easy to read was to the left was the office worker. They have just now started to test, you know, where can we gain productivity with our quote unquote office workers, however you want to define that. And and as time goes on, they're going to figure that out, right? There there are going to be se severely impacted areas of the office worker as that as that particular, you know, bubble uh you know, accelerates. Social services on the other hand on the other side which right now is more of a humanto human interaction you know I would not be worried about that I'd be watching that you know what changes in social service you know the analysis of the the people being treated using AI to be predictive of what might occur down the road and the interventions then that would occur you know things like that so everything's kind of at risk everything is about improving throughput, you know, get rid of the bottlenecks. And that's what you have to look for and not be surprised and and not dismiss a particular area because you don't think it could be impacted because we've all been surprised by what has [snorts] taken place. So, — yeah, lots going on.

[14:42] — All right, listeners, we're going to go to break. When we come back, we have a really special guest, Dr. Jeffrey Gladen, and he is a cardiologist who just thought there's a better way to approach longevity and health. And uh I think you're really going to love I know I do. His big theme is how to make a 100 the new 30 or what if you could you know have the health and wellness of a 30-year-old when you're 100 years old. So that's pretty exciting to me. I think back when I was 30 I was playing basketball 2 hours a day probably six days a week and playing football a few hours a week and running and doing all kinds of stuff that you know I'm I'm not quite that active today. So uh looking forward to that after the break. There are tales of abundance. We know that fitness is just as important as money or milestones. It's one of our fivefs. For lots of other taking care of my body while I build my life is one of the more time consuming and difficult goals to chase. That's why we're partnering with AG1. It's a daily drinkable habit. Less than a minute that's formulated with 75 plus vitamins and nutrients and designed to support energy, digestion, and immune defense. It even has a few grams of protein uh that we're all chasing these days. And if you want to try it with our affiliate link, you'll also receive a free AG1 flavor sampler plus vitamin D3 plus K2 with your welcome kit when you first subscribe. $72 value. Go to — Listeners, welcome back from the break.

[16:13] As promised, we are here with Dr. Gladen to talk about uh making 100 the new 30. And I love this concept. So uh Dr. Gladen, welcome and and thanks you for joining us. — Oh, my pleasure. Good to be here. Thanks, guys. — Jeeoff, good to see you again, too. — Yeah, likewise, John. — I think the last last time we saw each other, you were speaking on conference. You're you're a little bit of a celebrity in the space except for the little bit part. I think you're really well known and you talk about this cool concept of making a 100 the new 30. For those of our listeners that haven't heard that before, what do you mean by that? You can't really mean I can act like a 30-year-old when I'm 100, can — Yeah. [clears throat] Um, it's a little bit of a novel concept. You know, I think when people think about longevity, they've got a lot of different ideas of what that could be. Um, and you know, you hear people talk about, well, I want to I want to live to be 100. [snorts] I want to live be be 120 or 150 or 180 or 360 or 700 or, you know, immortal or whatever. what I what I discovered in my own journey was that it's very difficult for [clears throat] me to relate to that. So, every picture I saw of somebody that's 100 years old or 110 or 120, uh it's like gosh, that's not really what I'm going for, right? Uh it's not really what we're going for.

[17:27] And so, what [clears throat] we all can relate to though and what we all have at least a memory of if not access to is our youthfulness. And it's really so it really stuck with me that the idea of longevity and it's evolved from uh from here and I'll share that with you as well. But the idea is that if we can maintain a youthful body uh for the duration then that's really a big part of the gift. And so making 100 to new 30 I think is um is an admirable goal. Um, and and I also think that, you know, you can't ever get to something that you're not visualizing. So when I visualize myself at 100, I visualize myself as 30. [clears throat] And then that drives a lot of questions about, well, I don't feel this way, so what do I need to do to get there, right? It's rather than making peace with it. So it's it's meant to be both factual as well as inspirational as well as motivational as well as directional. So that's kind of the idea behind it. Yeah. What does a 100 look like for you? So when you visualize a hundred, tell me about that.

[18:31] — Yeah, so that's a great question. I, you know, the [clears throat] other piece of it for me is that I think that longevity represents the really the greatest opportunity humanity has ever had to sort of upgrade what the human experience can be. And what I mean by that is that when [clears throat] we're 100 years old, if we have um a 30-year-old body um and a 300y old mind, right? So now we've developed all the wisdom, all the tranquility, all the insight, all the equinimity, right? All the perspective, all the self-love. We've healed all the traumas and all the things that are holding us back. Imagine the contributions that we can make to the planet, to each other, etc. when we're working and operating from a place of a 30-year-old body with all the capabilities and a 300y old mind, right? So, for me, I get super excited about this because I think, you [clears throat] know, uh, every generation of humans has thought, well, it'd be nice to live longer. It'd be nice to live healthier. But, but I think the opportunity here is to kind of combine the two with this psychosspiritual wisdom that comes from the 300 or 3,000y old mind even. and having the youthful body to go with it.

[19:49] And so now you're combining something that humanity's really never had an opportunity to access before. And I think that to me is incredibly exciting. What can we accomplish if we go there? Right. So, — and you think that's Go ahead, Randy. Well, are you talking about somebody that is, let's say, somebody's 80 now or 60 now or whatever, when that person gets to 100, they can be like they were when they're 30 or are you talking more about a 30-year-old person being able to maintain that body? — Yeah, that's a great question, too. So, [clears throat] obviously, um, [snorts] one of the, uh, preconceptions and I think also misconceptions about aging is that it's a linear process because chronology is linear. Right? Every year it's another birthday. I'm a year older. I don't feel that much different. Right? It's it's linear. But in actual fact, biologically it's exponential. It's an exponential process. And there's tons of data that shows that. And we all intuitively know it, right? Like if you see, you know, that people age so much more between 70 and 80, 80 and 90, right, than they do between 20 and 30, 30 and 40. And yet we're handicapped in our ability to relate to it. Because if everyone on the call were to ask themselves, geez, what am I going to be like 20 years from now, right? What am I going to be like 20 years from now? It's virtually impossible for us to imagine we're going to be any different than we are today, right? So, we're in an exponential game of decline and we can't really relate to it even though we see it all around us. And so, we live in this kind of bubble of denial, so to speak, right? it's not going to happen to me. Even though we know it's going to happen to us, we still live in that bubble which which basically makes us complacent which actually keeps us from asking the right questions. And the right questions are, how do I maintain my youthfulness? How do I wake up 27 every day? I just had a birthday on February 28th. I was born in Um, you guys can do the math on that, but I wake up 27 every single day. And the reason I wake up 27 is because I'll be 27 this decade, 28 the next, 29 the next, and I'll be 30 when I'm 100. But waking up 27 every day enables me to ask myself, do I feel 27? And if there's some part of me that doesn't feel 27, I don't say, "Ah, but you're so good for your age. You just got back from a snowboarding trip. You're you're mountain biking better than ever.

[22:14] You're, you know, you're doing all these things." I never say that. What I say is what do I need to do to get back to 27 in every form and uh function that I have right and so it's the questions that drive all progress right and the interesting thing about humans is we go through go through life thinking that our life task is to find our answers right but it's really not about finding the answers it's about finding the questions even if you find something that you believe and hold to be dear like a religious uh you know conviction or whatever it's still the questions inside of that that will drive progress. How do I be more loving, more caring, more, you know, whatever. And so what I've discovered is that, you know, by waking up 27, then I can maintain my youthfulness. Now, the question you asked was, well, what about an 80-year-old? Well, because of the exponential decline, right, they're in a deeper hole, right, than somebody that's 70 or 60 or 50 or 40 or whatever their age, right? So, um, [clears throat] it's harder, right? And the interesting thing is that it's it's much easier for a Brian Johnson in his 40s to get younger than it is for somebody in their 60s.

[23:29] It's exponentially harder in your 60s or 70s or whatever, right? So, yes, kudos to Brian. He's doing a lot of great things. It's also fairly easy, right? Um, relatively speaking. So [clears throat] the thing is that I think technology is accelerating at such a pace that even for someone in their 80s that they're going to be able to access levels of function and activity. It may not be 30, but it's it's going to be so much better than what they had, right? And I think for people that are 30, I think the ability to maintain 30 is is going to be completely possible. And I think for someone like myself, um, I think I'll get pretty darn close. Um, and so I I'm I'm super pumped about that. But I also really focus tremendously on developing the 3003,000y old mind because regardless that also brings so much peace and joy and tranquility and love and caring, right? So that's a wonderful place to live. — Now, you've kind of talked about your four pill Go ahead, Anthony. I just got the four pillars.

[24:34] You talked about the four pillars just real briefly there and I know your four pillars because I've heard you talk about them before but let's let's let the listener know about the four pillars you have as you think about this longevity kind of it's a great mental map right and we need mental maps to be able to grab information quickly and then kind of progress from there. So give us your your mental model for the for the four pillars of longevity. Yeah. So the way that the way that we describe it is uh in terms of circles actually uh pillars circles doesn't really matter. It's nomenclature. But the point is that there's a life energy circle which is really the psychosspiritual space. And life energy is really the circle that binds all the other ones together. So imagine that you have a circle and it's called life energy. Well, what is life energy? Well, it's things that related to do you have a growth mindset? What kind of what kind of mental illness issues are you dealing with, right? What kind of traumas have you experienced that you're still living in reaction to? How good are your relationships? How are you developing wisdom? Right? What about um self-doubt and guilt and you know shame and things like this, right? And then how do you actually feel unconditional love for yourself? Many people don't feel unconditional love for themselves. And then getting to a point where you can feel unconditional love for yourself is very healing. And the reason this circle is so important is because when you take the stress out of living in reaction to your traumas, you actually heal those traumas and then transcend them and become grateful for everything that ever happened because it's brought us to this point with this much wisdom, insight, empathy, etc. Now you're actually changing the impact that your psychology and your nervous system has on your biology. One of the other big ones on that circle is feeling safe.

[26:16] You know, when you have the realization that nothing external to us can ever make us feel safe. There's no amount of money, no education, no, you know, book you can write or read or family you belong to or community or church or whatever you're part of that can ever make you feel safe. Safety is an inside job. Just like unconditional self-love is an inside job. Then that becomes a psychospiritual question. But once you're able to find safety in the midst of anything, right? And we know from history that everything could be taken away in a matter of moments quite honestly. So how do you give yourself ultimate safety, unconditional love and then how do you find your purpose, your meaning in life, right? So when you put all those things together, now your biology is functioning in a garden of neurological energy that is actually not tearing it down with stress, but actually building it up with love and joy and creativity and satisfaction and rewarding relationships, right? And so this is a massive missing piece. We focus on the biochemistry. Well, we're going to adjust your hormones. We're going to adjust your your peptides. We're going to fix your gut. We're going to do this. We're going to do that. We can do all that but it's the environment that it resides in in the psychosspiritual space that drives so much of the decline in the first place and conversely it can actually help reverse all of it. So that's the number one circle life energy. Number two is longevity. Longevity is basically looking at the hallmarks of aging, right? And we're up to about 12. I think there's probably about 16 currently myself uh when I look at it. But the point is that these are the actual biological processes that are driving and accelerating aging. Right? And it's not just hormones. It's telmir shortening. It's scinesscent cell burden. It's inflammation. It's gut dispiosis. It's you know DNA damage that's not being repaired. It's proteins that aren't being made or folded properly or disposed of properly etc. So these hallmarks of aging mitochondrial dysfunction for that matter oxidative stress etc. So these these hallmarks of aging which are both phenotypic expressions. In other words, they're actually expressions of aging, but they're also drivers of aging, right?

[28:19] And they all play together. They all play off each other. So when one starts to fail, it impacts four others. And those four others failing impact another four. And then that feeds back to the initial ones. And so it's this spiral. And this is why it's an exponential decline. It spins up like a tornado. And what happens in most longevity practices is they not focused on the hallmarks. They're focused on the phenotypic expressions, right? We're going to we're going to make you feel better, look better, your muscles will be stronger, we'll heal this, we'll heal that, we'll fix your gut, etc. But we're not really relengthening your telomeres. We're not really optimizing mitochondrial function. We're not pruning scinesscent cells. We're not modulating their balancing that. We're not augmenting DNA repair, you know. And when you go after that circle now I call it getting at the root cause of the root cause of biological aging. And then there's health. The health circle is basically all the functional medicine things we know about. And that's root cause medicine. But longevity medicine is root cause of root cause medicine which is why that circle is so important. And then the fourth circle is performance.

[29:21] So when I'm 100, I want to be fast, agile, strong, quick, balanced, great cardiovascular capacity reserve flexibility, right? I want to be able to do anything I want to do. I want to run down the stairs. I want to snowboard. I want to, you know, roll in the grass with my great great grandkids, whatever it is, right? I don't want to have any limitations. And in order to do that, if I'm going to do that at 100, I need to do that today. And if I'm going to do that today, then I need to train for that. And the interesting thing is that the workout that you did, you know, when you were 18 isn't the workout you need in your 30s. And what you did in your 30s isn't the one you need in your 40s. and what you did in your 40s isn't the one you need in your 50s. You have to keep adapting your workouts to actually get to the goals of what I just outlined there. So, there's a lot of um again asking the right questions. How do I maintain that 30-year-old body, right? And you realize that lifting weights and going for a run, which worked when you're 18, is not going to work for you when you're 65, right? So, — so if I've got a 30-year-old body, it makes sense I should have a 30-y old workout. But you're saying, "No, no. If you're 70 years old and you want a 30-y old body, you've got to do a different workout when you're 70 to get there than when you're 30." Tell me more about — Yeah. So, [clears throat] you know, I I I have this conversation with clients all the time, and I tell them really all of life comes down to one thing, right? Just one thing. And everybody looks at me like, "Really? Just one thing? I mean, yeah, just one thing."

[30:48] And it's optimizing our nervous system, how we think, how we feel, what we believe is true, what we think is possible, how we move through space, right? All of it. The traumas we've not resolved, the love, all of it, all of it comes down to the nervous system. When you optimize a nervous system, you understand that when you're training, you have to train your nervous system. So when you're training, you're training the nervous system to activate the muscles that need to be activated. And that happens naturally when you're 18. But when you're going through life, nerve and nerve uh muscle inter intervention or intervation rather uh can decrease [clears throat] and so you've got to actually stimulate that. So lots of balance training, lots of um isometric exercises to activate things, right? You've got to you've got to build the cardio back. You've got to build the strength, the flexibility. It doesn't just happen. So you can have a 30-year-old body, but the way you get there is not the same as it would be if you were 18 years old, if that makes sense. Yeah.

[31:54] So the fifth the fifth area that we've added since I wrote the book is the environments that we reside in. And so when we think about the environments really we all live in four predominantly, right? Home, business, uh business, travel, and vacation, right? That's at least 96% of it. Um and so [clears throat] architecting each of those environments to support the mission to make it as effortless as possible to stay on track with what you're trying to do. And it takes, you know, um conscientious architecture to do that. I've had clients that were doing great. They said, "Oh my gosh, I couldn't believe the progress I was making. I felt like I was 30 years old again. I could do anything." Then we went to Italy for 3 weeks and the wheels came off and I came back and you know all this stuff. So it's like, "Oh, okay. Well, we need to architect each of those." So we actually are hiring an implementation specialist to help our people implement across the five circles in all four of those environments, right? So that that's a really key piece. Um how do you make it easy, fun, rewarding, uh how you mix it up so it doesn't get boring, you know, that kind of thing. So — that's home, work, business, travel, and — Cool. Love that.

[33:08] Yeah, I'm — trying not to jump all over Randy and Anthony. There's so much to do here. Anthony, go ahead. — Well, um I had a question, but when you when you started Jeff with the uh Dr. Jeff with the uh [snorts] the circles and you talked about the outer circle, um it it struck me that that's the most difficult place to make progress. Um it it's it made me think, boy, do I need some psychotherapy, some counseling? uh to really find, you know, what's troubling me, why why I don't feel the way I should feel and so forth. So, how do you how does your team attack that or deal with that? — Yeah, it's a great it's a great question. So, we work with therapists um and we have them on our team. They're not employed by us, but they're they're people we refer people to uh depending on what somebody uh someone's needs are. And so we can assess where people are in the life energy circle through conversation, right? We can get a sense. And I'm I'm actually I'm an INFP on the MyersBriggs, right? So I'm very intuitive, very perceptive, and I can read people's energies very well. And so I can get a feel for people very quickly in terms of where they might be struggling. Um, and so with that, then we also do uh testing. So, we're measuring I don't know if you're familiar with a brain tap. There's a brain tap neuroche is what it's called. And basically, it's a computer and we put clips on people's wrists and it will it will actually in 5 minutes it will read the status of their nervous system, the sympathetic parasympathetic nervous system balance, how deep the stress goes into the neuro hormonal uh component, uh cardiovascular risk, brain assessments, things like this. and it'll actually give them a neurological age, if you will. Um, and so it's possible to document this not only through conversation related to, you know, prior experiences or or that kind of thing. Um, but also in terms of how much stress somebody's carrying in their system. And what we find is that um, a lot of people are unaware of the amount of stress that they carry. Um, you know, we had a woman in here not long ago that comes to mind who um said, "I'm not really under any stress. My husband, you know, is extremely successful and, you know, I I don't have any real stress. Uh, love my grandkids, etc." And and I looked at her profile and it told a completely different story. And I said, "Well, there's something going on here uh where you seem to be carrying more stress than maybe you're able to perceive right now." and she said, "Well, I'm having some trouble with my daughter-in-law."

[35:54] It's like, "Well, let's talk about that for a minute." It's like, "Oh, okay." And then and then it got into uh her birthing order. She was the oldest. She was always responsible for the other kids. Now, she's having some conflict with her daughter-in-law who doesn't really want her input on the grandkids. And so, she's actually carrying more stress than she realizes. And what happens for a lot of people is they're they're wearing a backpack and they've worn the backpack for so long that they don't really know what it's like to carry it anymore. It's just like it's part of them. And what we do is we help people identify that they have a backpack and then we can actually help them take the backpack off. And when people are able to do that through a combination of speaking with a therapist or or doing other things, you know, uh modifying their nervous system, their balance between sympathetic and parasympathetic with brain tap or meditation or other things. Um some of the some of the folks have even gone on to do psychedelic assisted therapies um with practitioners to you know help have some breakthroughs and and out of all of that people can take the backpack off and all of a sudden it's like oh okay I get it now and and their scores will improve dramatically because we can measure how the stress has been dissipated. It's really remarkable and they're very encouraged by it. So, while it can be in a traditional medical practice the hardest thing to get to, Anthony, to your question, in our practice, it's one of the easiest things to get to and it's really one of the things we go straight at right from the get-go because we know how important it — Well, I've never I've never had a doctor really spend any time I don't know about Randy and John really spend any time talking about quote unquote my complete mental health. It's more about how you're feeling, how the kids, — that's it. you know that surface that surface level amount of stress is not really a deep dive. I mean, my, you know, I had a personal experience yesterday of a full day of joy with my uh my grandson started the morning. I'm out here in Arizona babysitting and started the morning at the park flying a remote control airplane, a — a uh a um a race car, a a Formula 1 race car thing. And — I went off to what's called Andre, which is a they have a go-karts and video games and everything else.

[38:13] — Well, When I got home and we sat down to put the kid down, my wife and I said, "Geez, that was brutal. That was hard. That was really difficult." So, all that joy, the end of the day was, "Oh my god, can I can I can I actually do that again?" And I'm in pretty good shape. I'm 69. I'm in pretty good shape. — Um, you know, and I exercise every day. I do a lot of the things we talk about. But you know, even even when you have a joyful moment and you're still at the at the end, there's still stress and tension and worry about the next day and how we going to keep up with you. So — yeah, I think you know it it depends on uh essentially on basically how you build the nervous system. So one of the things that you're talking about is u you know having joy and feeling love and all those kinds of things. And when the nervous system um is actually deconstructed and reconstructed, you'll find that it's not really about how much love and joy can you hold.

[39:18] It's not about that. It's about how much love and joy can flow through you. You become a conduit for it. You're not trying to create a reservoir of it. Uh it takes it takes energy to hold a reservoir. It's easier to let it flow through you. And then when you understand that tomorrow you have the opportunity to do the exact same thing again, but you're not trying to hang on to it, right? It's all the psychic energy to concentrate on him and the car and all that stuff. But if you go into a relaxed sort of just I'm here to enjoy whatever happens, you'll find that at the end of the day, you feel more energized than you feel drained. It's a different It's again about training the nervous system. Um so yeah. — Well, thanks for thanks for that free free advice. I appreciate it. — Yeah. Well, there's there's good stress and bad stress, right? Just like when you're lifting weights, there's good there's good ways to exercise. So, talk about like the the kind of good stress versus bad stress and what you talk to your clients about. — Yeah. So, horatic stress is what you're talking about here. And this is basically a physical stress. It even could be an emotional challenge, but it's a it's a physical stress that is enough to cause your body to react and get stronger because of it, but not enough to break it down to the point where it's damaged permanently. Right?

[40:29] And so hormetic [clears throat] stresses are super important, right? And it's super important to stress the nervous system also, you know, playing games, puzzles, you know, doing stuff like that, ch learn the piano, you know, whatever it is. Stressing the system um keeps it youthful. That's why balance training is so important, right? Uh doing it with your eyes closed, right? Being on a balance board or whatever else. It's all of these things are challenges to the system. And you have to realize that you're challenging not only the muscle and the joint and the tendon, but you're challenging the nervous system ultimately. And when you do that and you do it in a variety of different ways, then that's how you get stronger. I will say that when it comes to uh to how you navigate life, one of the um illustrations that I'm using for people in the practice now, I'm actually showing them a video of a mogul skier. And I don't know if you guys have seen professional mogul skiers, right? how they go down through those bumps, right? And when you look at a professional mogul skier, their their body is down the fall line. The upper body is still, the head is looking not at the mogul in front of them, but looking all the way down the hill, right? And their legs are basically bouncing back and forth over the mogul, right? And what happens if you see a novice mogul skier, right? or like me if I'm on a snowboard in a mogul field I'm like bouncing here and bouncing there and trying to catch myself and you know it's like a yard sale right and I tell people that the idea for us in terms of uh visualizing what we want our nervous systems to be like is to be like a mogul skier where there are many different obstacles slash opportunities in life every there are no problems there only opportunities so now you have all these different opportunities to kind of joyously go through the mogul field But your upper system and your nervous system is calm.

[42:21] You're simply navigating it, right? It's a little bit like Kiana Reeves in the Matrix. A bullet gets fired and you basically just lean back and watch it go by. It's like, "Oh, well that's interesting. I don't have to take the hit. I don't have to react." Right? So when you when you basically master the nervous system in terms of how you perceive the world and also how you move through space, all of a sudden you have a completely different life. It's really a beautiful thing. Well, how do I get started? So, if I'm if I'm listening here, first time really thinking about this, I might be, you know, entrepreneur who's younger in my journey or someone who's been on the journey for a while, but haven't thought about it with this particular kind of point of view. How do I get started? — Um, well, there's lots of ways to get started. Then, we have a we have our own podcast, the Glad Longevity Podcast. We over 320 podcasts out there now. I think I've been a guest on many podcasts. Um, — amazing podcast, by the way. Like to I just want to like for half a second just it's such a great place to go for knowledge, for learning, for cool stories. Like if you haven't checked out Jeffy's podcast, like do it today.

[43:25] Amazing place to get information. Sorry. Go ahead. — No, I appreciate that. Yeah, it's fun to do. And then and then the book 100 is a new 30. It's on Audible as well if people like to listen to it. I read the entire book. I wrote the entire every word in the book myself. Um this was before AI. Um just before AI came in. Um, and [clears throat] so that's there. And then if people are really interested to uh engage with us, they can reach out through the Gladen Longevity uh website and they can book a call to see if we might be a good fit for them. Um, and we have people in their 30s and 40s and 50s and 60s and 70s and 80s, right? We have people with all kinds of either issues or non-issues. You know, we have young people that have been very successful with their business and sold it. Uh we have people that are still in the middle of their working years. Um all kinds of things. And we've we've helped athletes. We have a woman right now that's joining us who's 45 that's has set a world record in um she's the only woman to have ever summited the second highest peak on all seven continents. And now this year she's going to complete the highest peak on all seven continents. And she's 45.

[44:31] It's like you know what? I'm starting to lose my edge here. Come in and help me. So it's like okay great. Come on in. So we can optimize, you know, we're all about optimization and we help people optimize. The first thing, however, for somebody to understand is that when you're going to really optimize yourself, it's not about what is somebody going to do for you? What are you going to take? What are you going to do? It's really how do you deconstruct where you are? And the analogy I use for business people is if you're going to buy a business, the first thing you're going to do is you're going to deconstruct that business from stem to stern. What's the cash flow? What are the liabilities? what's the you know what's the pipeline you know all the different things what's the you know how's the material come in and all the what are the challenges what are the you want to know everything about it once you deconstruct it it's like oh okay now I see that it has value and I see that these things need to be mitigated and these things need to be optimized it's exactly the mindset we take it's like let's understand you deeply first then actually we can actually show you how to start to move forward so that's really the approach that we use and that's it's a custom It becomes a custom fit for each client that we work with because of — Are there two or three things if someone's, you know, not able to get to see you right away, they're going to read your book? Like three two or three things that everyone should consider doing right away.

[45:48] — You know, I think [clears throat] um there are some things that are universally good, right? So I I would say that um you know using a device like BrainTap and I don't have any financial relationship with them, right? So, this is not me trying to sell something, but BrainTap is a uh photobiomodulation and binaural beats device that you can wear that will actually entrain your brain into a meditative state. Whether it's a deep theta state, like just before you're going to fall asleep, can help you sleep and put you into delta, so you're in a delta waveform to fall asleep. You can go into alpha, which is a typical meditative state, or gamma, which is a flow state before you go play golf, and you'll play golf better. But you can start to learn to control your mind, right? Learn to control where your mind is. And you can go into a meditative state. And the goal is once you learn how to control your mind, then it's not just about, well, I meditated for 10 minutes and now I'm going to go about my day. It's like, no, I'm going to go through my entire day in a meditative state. And then you become a mogul skier, right? You become a pro mogul skier. It's like, oh, okay. You've taken a lot of stress out. So that's that's something I think everybody can do. Um I think you know molecular hydrogen we do have a molecular hydrogen product that we think is special. It's in uh basically imprinted with energy or chill that's you know universally good.

[47:10] Hydrogen seems to be un universally good for people to manage oxidative stress things like that. Um you know diet um is a funny thing. The problem with diets is that they all start with a food and in actual fact you've got to start with the individual. You know what are your sensitivities? What's your gut? What do you like? you know, what's your gut biome, how are you digesting food, all these things, right? So, until you till you deconstruct, — um, you know, you really don't know what to recommend. And so, we're big fans of deconstruction. Uh, we find that we we're much more precise and we get much better results when we do it. Go about it that way. — Yeah. Assess before you do the work. That seems pretty smart. Not everyone does that. They just want to do the work sometimes. Making that assessment. — Come on in and we'll give you extra. Come on in. We'll give you peptides. You know, come on in. We'll do this. We'll do that. Right. jump in the cold, do the sauna, right? I mean, all those things have a place. We We have all the technologies. It's We have all of them. — the question though is what do you actually need? Uh and what's going to get you the biggest bang for the buck? — Well, all of us can um can afford and Brian Johnson can afford, you know, whatever whatever he needs uh or wants to give a shot at. But um you know most most of our listeners and most people in our lives are you know looking for um the I won't call them shortcuts but you know things that they can do. So — can you can you weigh in on um a lot of the some of the you know currently popular things that are making the rounds like vibration plates and red light and sauna.

[48:47] — You know I you touched on peptides and so forth. All I'm sure they're all good, but if you were, you know, if you were advising a a 50-year-old who's on a moderate income and, you know, in in decent shape, but wants to get going, what what anything anything that they should just stay away from that's kind of in the zeitgeist that is just u sham kind of a sham? — Well, I don't think any of the things that you're mentioning are sham products, right? I think you know red light sauna there's great data on sauna you know Swedish sauna there's you know the study that came out in 2015 and the American journal of medicine that basically showed that um if you took you know men between I think it was age 40 and 60 and followed them for 20 years and looked at sauna usage right at 180 degrees for 20 minutes or 19 minutes actually and you looked at how they did that the guys that used it 4 days a week or more had a 55% reduction in uh Alzheimer's and dementia, right? 50% reduction heart disease, 40% reduction all cause mortality and cancer. It's hard to it's hard to compete with that, right? So sauna is pretty much universally good unless you've got some heat induced rash or you've got some, you know, some other situation where maybe that's not the right thing, right?

[50:03] Um so those things are good. You know, cold plunge can be helpful. You're basically stimulating a ton of dopamine. If you've got cardiovascular disease and high blood pressure, you may want to actually think about that twice because you're going to spike your blood pressure when you hit the cold water. Um, if you've had a stroke or a bleed or an aneurysm, it's probably not the right thing, right? So, again, you need to actually understand who you are before you just jump into the ice water. Um, you know, I think hormone optimization is critical and hormone optimization is really done poorly. People go in and they get a testosterone measured and an estrogen and it's like, "Okay, well, we're going to put you on testosterone now." And, you know, we don't want you to have too much estrogen, so we're going to put you on an estrogen blocker. And and then it's that's they just leave them there. Well, it turns out that men need estrogen just as much as women need testosterone. And it's not really about the levels as much as it is the metabolites that determinate your risk for prostate cancer, breast cancer, endometrial cancer. So unless you're looking at the whole picture and deconstructing it, just to go to a tea clinic and have them put you on testosterone and an astrosol is like one of the I mean it's it's kind of like playing Russian roulette quite honestly.

[51:14] So I will say that sexual activity is a good thing, right? It's been shown that — say that again real quick. I just want to make sure we all hear that really — Okay. Having lots of sexual activity is really good. It's really really good. Yeah. Let me say it one more time. sexual activity is wonderful because um — Dr. Jeffrey Gladen, everyone. — That's right. All right. Yeah, we write prescriptions for it all the time. So, no, [clears throat] the point is that men that have more than 20 ejaculations a month have a significantly decreased risk of prostate cancer, right? When you actually um have sexual activity, you're releasing oxytocin. Oxytocin is a molecule that not only makes you feel connected to the person you're with, but it also has so many benefits. It lowers stress. It relengthens telomeirs. It increases autophagy. It decreases inflammation. I mean, so better connection, right? We live in a digital world. Well, you're kind of connected to our phones, but we need to be connected to each other. I was just reading something where we also need to be connected to nature, right? It doesn't cost anything. But the trees, when you're out amongst the trees, they're actually letting go molecules into the air that boost your immunity. Isn't that fascinating? Right. So there's so many things about being out in nature that are good for us right now. If you've got, you know, uh predisposition to to skin cancers, you know, you can take something like Helioare and still take get out in the sun. Helioare polypodium glucomus. It's amazing molecule. Um if you have skin cancers, we've seen amazing results with that. But you can protect yourself from that. But getting out in the sun, right? D, you know, getting your feet in the ground, all these things, these are free, right? So if you're talking about what can somebody do on a low budget, the other big thing is it's not so much what you add as what you take away. You know, look at the things you're eating, the things you're drinking, the air that you're breathing, right? U how much time you're spending in front of blue light, things like that. You know, m migrate that towards, you know, more of a plant-based diet, right? Where you're getting many phytonutrients. And we think that the carnivore diet is kind of faulty in a way that you're getting so much methionine that you're actually accelerating aging, right? So, and your body likes to be keto part of the time, but not all of the time, right? The biology doesn't want to be pushed in a corner. It's really an economy of balance. It likes to cycle through different states. Wants to be fed. It wants to be fasted. It wants to be have plenty of protein. It wants to be protein deficient. It wants it wants all these different cycles. And so, I think that's really important. And there's a a weird thing out there about, you know, older people need to just pound protein.

[53:51] Well, that's really kind of crazy, too, because high protein diets are associated with accelerated aging, more mTor activation. So, you really want to get the protein that you need, but you can actually get it through something called perfect aminos where you get all the essential amino acids and you don't have to eat all that protein. And then, if you're hormonally optimized, you can make muscle and connective tissue and things like that. So, there's lots of different things out there that need to be done well. Um, but really, if you're listening to this, it's like, oh, let me get outside. let me take out the things in my diet I know are hurting me and uh let me have more love in my life, right? And those are those are like massive and then let me the first thing is let me go get my hormones tested, right? We find also a lot of subclinical hypothyroidism out there. We measure resting metabolic rates on everybody. We find thyroid blood tests are misleading all the time. So, if somebody doesn't feel like they have much energy, one of the first things we do is say, "Okay, let's look at your mitochondria and everything, but let's do a resting metabolic rate and see where your thyroid set." Right? That you can do that for a few hundred, not terribly expensive. So, anyway, those are some things off the top of my head.

[54:59] — How do you um real quick, John, um um bioididentical hormones versus uh synthetic? Yeah, you want you want to use bio identical particularly if you're a woman um you know with progesterone and progesterines of course have increased breast cancer risk. Progesterone decreases breast cancer risk. So you want to be on bioidentical stuff. Yeah. — And then topical versus oral those are all questions to be answered you know from deeper medical understanding for the individual right or injectable. Uh so those are all you know they all have their place is my point — right? And along those lines, clean up the debate about like full body MRI. Like there's there I think there's two sides to that debate about whether it's a good use of time, energy, money. But talk us through that. — Well, I think you know we get full body MRIs on virtually all of our clients at some point because we want to know is there a brain aneurysm? Is there a abdominal aortic aneurysm or is there you know some cyst in the liver or whatever that we that we just want to know about, right?

[56:03] um because you know people will have funny stuff show up. Um on the other hand, I think the biggest lie about these imaging scans is that oh I don't have cancer. My MRI was clean. I don't have cancer. That is like it's worse than a lie. It's actually misleading because cancer is microscopic. MRIs have a resolution of, you know, a few millimeters, but it you you can't see cancer cells on an MRI scan. Um, by the time you see cancer cells on an MRI scan, it's you've got billions of them, right? And they're probably in your bloodstream. So, we need better screening tools. There's a new we we send stuff over to Greece to have it look for circulating tumor cells. There's another place in Dallas that does a similar thing. There's um a new test coming out that we're excited about actually developed in India that can uh detect stage one cancer. I will say that Grail is a terrible test. It's almost useless quite honestly. It has a 70% chance of picking up stage one cancer. So we don't we've never liked Grail um or Gallery test. Uh so but the idea that you can get a scan done and be told that you're clear of cancer is is the worst information you can get. Uh it's tragic quite honestly. Yeah.

[57:23] — Particular if you're survivor. — Yeah. Particularly if you're a cancer survivor. We had a guy come in with uh previous melanoma recently on the left side of his chest four years ago. It was removed. It was removed. Told everything's clear. Everything's fine. We said okay well that's great. let's send some blood over to Europe and see what we see. So it came back melanoma circulating melanoma cells, right? So I was like, okay, well, let's do the DNA deconstruction on. Okay, it's actually cancer. So let's send for a PET CT. Now we send him for a PET CT, right? He's got a hot note under his left axilla in his left armpit, right? So now he's going down to Mexico and he's getting very advanced immune therapies and some other things to kind of augment this. But this is the kind of tragedy people people are told that they're clear and then how many times have you heard they show up with mets all over the place 5 years, 6 years, 4 years, 10 years later. It's like it's it's the it's the worst it's the worst thing that medicine does, I think. Uh is to tell people they don't have cancer when we really don't know unless you do more sophisticated testing. Yeah.

[58:27] — Yeah. So, a long way to go in science, that's for sure. And hopefully it continues advancing at the accelerating pace that it's going. So — that's great stuff. That was great — Can you go can you go back to the protein discussion? We've been in recent discussions in our peer group. We've been going back and forth of on all kinds of things that we're hearing and you know what's what's the what's the latest and so on and so forth. And you mentioned something I'm not I'm not familiar with relative to um getting the benefits of protein without actually, you know, eating steak three times a day. Can you talk more about that? — There's a product. — Yeah, there was a product that was developed by uh a physician actually out of Florida who uh was an Iron Man and I think he's done like 50 different Iron Man races and he ended up developing a uh protein replacement product called Perfect Aminos. Uh it's it's just amino acids and it's all the essential amino acids in a proprietary ratios. If you eat an egg white, which is nature's perfect protein, right? Um, you get about 49% of that protein actually goes into building protein.

[59:37] People are eating protein because they want to build protein in their body. Right? If you're if you're eating collagen, only 22% of that goes into actually making collagen. The special thing about collagen is that it actually stimulates collagen production. So, that's an interesting thing about collagen. Whey protein, right? only about 31 or 32% of that goes into actually making protein. So you're exposing what happens to the rest of it? Well, it goes into carbohydrate, right? Or it could even go, you know, be processed through the kidneys, things like that. So the point is that if you want to build protein in the body, which is really what you want. You don't care if you're eating protein. What you care is if you're building proteins, right? Muscle and tendon, ligament, things like that. So if you take perfect aminos, 99% of it goes into building protein. So now you don't have to expose yourself to all of the excess protein, right? And the mTor activation that comes from that. You can just use the perfect aminos. And if you have kidney disease, you don't want all that protein in your system, right? So then you can use the perfect aminos and um get what you want without having to saturate yourself with like tons and tons of protein.

[1:00:46] — And that's vegan. It's a vegan product, — Yeah. Yeah. It's not That's right. That's right. That's right. So, per Yeah, perfect aminos is what it's called. It comes in a powder. It comes in in tablets and uh — Yeah. So, we use it. Um, you know, sometimes you want to be anabolic, right? Sometimes you want to be catabolic. When you're anabolic and building stuff, then that's a good time to be taking the perfect aminos, lifting weights, you know, using peptides like CJC1 1295 to stimulate growth hormone release and things like that. That's all wonderful then. But if you're fasting, you don't want to be doing that, right? You want to be catabolic. So now you don't want all the mTor activation. You want to be activating AMPK. So you're fasting, you're doing cardio. You're, you know, using things like bourberine or metformin to activate which is then stimulating all the recycling, all the autophagy. That's where the NMN comes in for DNA repair and things like that. Right. So there's a there's a sophisticated way to actually think about this. Um, yeah. and and your and your the the services that you do, the the people that come to you and and are on the program and stay on the program, they have counselors that are working with them, talking to them about the science that obviously is zipping over my the top of my head. Is that that the the is that your program is all about?

[1:02:07] — Yeah. So, to work with us, you don't have to understand all the science that we understand, right? I mean, there are very few people that that do that that come in from from the lay population. Um and uh and yet what we try to do is to we use the five circles basically as a template. So we're going to test we're going to deconstruct you across all five circles. Then we're going to actually find out the results across all five circles. We'll share those with you in terms of what we found. But then we distill it down into what's the action blueprint for each of the circles. Right? And we make it digestible. Right? People can't do a hundred things. And what we've discovered is that if people are overwhelmed, they disengage. So what you want to do is you actually want to feed them enough information to be actionable, but also encourages them to continue to be compliant. Then you can layer things in as they build up their own uh systems for it. Right. And so we have people that help with that. Yeah. Texas to get your services or do you expect people to come up to Dallas and — Yeah. So that's a great question. So medical legally in the state of Texas, we have to see people in Texas um at least once in a year to establish a physician patient relationship. We call them clients, but it's really in the eyes of the Texas Medical Board, it's a physician patient relationship. So people do come in and what we found is that in order to do the deconstruction, it's much more efficient to come here and let us do it over 2 days or 3 days.

[1:03:38] you can't I mean otherwise you'd be running all over the place trying to get this stuff done and it's done poorly and it's not done right and all that kind of stuff. So anyway, people come in and spend two or three days with us. Um this woman that I just told you about that's going to summit all these mountains is coming in this week uh for a couple days to get a bunch of stuff done. Then she'll go home. We'll get her results. We'll have some results for on day two from day one. Um some of the biometric testing and then u we'll get some of her other stuff back, genetics and whatever else which will take up to five or six weeks potentially. Um but then we'll start feeding her information and again across the five circles so that she can start taking action and we can start getting her going knowing that she's going to be doing this uh you know extreme u athletic activities. we start building the things that we know are going to be most crucial for that from the get-go and then we'll work into the longevity pieces as well. So yeah, do — you do continuous glucose monitoring? Is that part of the program or is that really not necessary? — It is. — No, continuous glucose monitoring is useful. The problem with continuous glucose monitoring is it doesn't measure insulin levels. So, we do 2-hour glucose tolerance test with insulin curves on every single client because it's stunning to see actually even somebody with a hemoglobin A1C of 5.2 and a fasting blood sugar of 89. You challenge them with 75 grams of glucose, they may be diabetic for an hour, right? Or two hours. They may have fasting insulin levels that are even normal at two or three and they may shoot up. Instead of shooting up five times, they may shoot up 25 times. We had a young girl in here that wasn't diabetic. Normal uh she was uh just graduating high school 18 came in with new onset MS. Um and we basically hemoglobin A1C was like 5.2 fasting blood sugar 89. We said we think you should do a glucose tolerance test you know just morphologically and um and u hereditary wise it appeared that that might be useful. Um we did that and uh her blood sugar shot up to over 200. Her insulin level just so people listening and normal insulin level should be about three four maybe five something like that. It should go up maybe five times when it's challenged. So maybe up to 20 or 25 somewhere in there. Her insulin level went up over 200.

[1:05:54] — Right. So this is a young woman who is basically charting a course for You know the beta cells of an 18-year-old can push out that much insulin. But how many years can you do that for? It would have been completely missed by her doctor. It would have been completely missed by by everybody, right? So a CGM can be good because sometimes we'll see that people control the sugar beautifully, but it takes a ton of insulin to do it. And the insulin is aging us. It actually causes thickening in the arteries, right? It increases scinsesscent cell formation. It's activating mTor just like IGF-1 is. So it's about looking behind the curtain behind the curtain. This is why the deconstruction is so critical to get right because otherwise you think you know what you're doing and you're and you still don't right and that's what we're trying to solve for. Yeah. — I think you know that's if if my big takeaway today is going to be like, you know, diagnosis before treatment, right? Like that sounds so incredibly obvious, but you know, talking with your medical provider and not just get diagnosis, but get the right diagnosis where you're engaged with the provider and and you're doing the things that work for you, not the things that work for people or for the statistics. So, this has been great.

[1:07:07] I mean, we I think we're gonna have to have you back on. We're going to want to dive deep into a couple different topics for sure for people. It's just it's an amazingly dense set of material. But I think the the big good news takeaway is that if you want an abundant and long life, we now have answers today that we didn't have in decades past, we can do something right now, regardless of your age. And there are experts like Jeff that you can turn to and and jump in right away. So, uh, great. So, if someone wants to come find you online, Jeff, where are they going to find you? — Yeah. So, if you go to gliden longevity.com, you'll get access to all the resources. Uh, there is a new website coming out, I think, in the next six weeks. That's uh we've been working on pretty hard. Uh, but the one that that we have there now will will lead you to the social media. It'll lead you to the book. It'll lead you to the supplement shop. It'll lead you to uh, you know, scheduling an appointment if you want to talk with us, if you're interested to work with us. Um, people work with us many times for a year at a time. So, there's a membership fee, which is also an insurance policy as well. we sort of go at risk. You pay us a fee and then no matter what turns up, you're in a car accident, you develop cancer or an aneurysm or stroke or whatever, we're there to take care of you all the way through. Um, and then there's testing on top of that. So, the investment can be um, for some people can be significant, for other people it's not. Um, but it's it's it's really the best investment you can ever make, right? Is maintaining your health and your vitality. I mean, the return on investment there is massive. So, — yeah. What would you pay for 10 extra years of life, right? That's so that's amazing. And so check out the podcast as well. You'll see all that in the show notes. Jeff, thanks so much for being here. It's been amazing conversation.

[1:08:42] Expect an invitation back very soon. — Yeah, I appreciate it, guys. Great to chat with all of you. Thank you. — Terrific. Thanks. — Thank you. It's been fantastic. — Listen and subscribe to the podcast wherever you get your podcast. Click follow for more content like this or go to talesofabundance.com to join our community and get free tools.